EVALUATION OF Cassia singueana EXTRACT ON STOMACH HCL PRODUCTION AND GASTRIC EMPTYING IN RATS
نویسندگان
چکیده
Investigation of the effects of the extract from C. singueana leaves on stomach hydrochloric acid (Hcl) production following histamine administration and on gastric emptying was carried out in rats. Cassia singueana extract (CSE) at 250 and 750 mg/kg significantly (p<0.050) decreased both gastric free-Hcl and total acids as well as the quantity of meal emptied from the stomach when compared with solvent control. The extract at 250 mg/kg exerted a significant decrease in gastric emptying more than cimetidine (100 mg/kg). CSE contains alkaloids, tannins, sterols and terpenes but no flavonoids, saponins, carbohydrates, reducing sugars, starch nor polyuronides.
منابع مشابه
Gastroprotective effect of the crude methanol extract of Terminalia avicennioides in rats
SuleIMan, M. M., I. O. ROManuS, S. YuSuf: Gastroprotective effect of the crude methanol extract of Terminalia avicennioides in rats. Vet. arhiv 77, 345-354, 2007. aBSTRaCT The effect of different doses of methanol extract of terminalia avicennioides (Combretaceae) on acute mucosal damage induced by 0.6 M HCl and on mucus production in the stomach of rats was studied. Animals treated with t. avi...
متن کاملEvaluation of the Anti-ulcer and to Buettneri in Laboratory Animals
The anti-ulcerogenic potential of the leaf metha Berger was investigated using three methods of gastric Wistar rats (150-200 g) and mice (20-25 g): 1. HCl/e Indomethacin-HCl/ethanol-induced gastric lesions, a gastric lesions. Mice were used in acute and sub acute t of the extract of Aloe buettneri to the rats and mice (50 prevented the formation of acute gastric lesions induc techniques. The do...
متن کاملCYTOPROTECTIVE AND ANTIOXIDANT EFFECTS OF THE METHANOL EXTRACT OF EREMOMASTAX SPECIOSA IN RATS. Perfusion
Background: Ethno-botanical information shows that Eremomastax speciosa is used in the traditional management of various stomach complaints including gastro-duodenal ulcers. Materials and Methods: In this study, we tested the cytoprotective potential of the whole plant methanol extract (100-200 mg/kg, p.o), against HCl/ethanol, absolute ethanol, cold/restraint stress rats, and pylorus legated r...
متن کاملAntiulcer and gastric antisecretory effects of Landolphia owariensis extracts in rats.
Water, methanol and chloroform extracts of Landolphia owarensis were investigated for their effects on gastric acid secretion and ulceration in male albino rats. Two models of gastric lesion induced in experimental Wistar rats-HC1/ethanol-induced gastric lesions and Pylorus ligation-induced gastric lesions-were employed. In both models, the antiulcer activity of LA was compared with that of cim...
متن کاملCytoprotective and antioxidant effects of the methanol extract of Eremomastax speciosa in rats.
BACKGROUND Ethno-botanical information shows that Eremomastax speciosa is used in the traditional management of various stomach complaints including gastro-duodenal ulcers. MATERIALS AND METHODS In this study, we tested the cytoprotective potential of the whole plant methanol extract (100-200 mg/kg, p.o), against HCl/ethanol, absolute ethanol, cold/restraint stress rats, and pylorus legated r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2010